Cancer types More. Prostate cancer forum. Prostate cancer forum requires membership for participation - click to join. Community News. Replies 15 replies Subscribers subscribers Views views Users 0 members are here. Prostap vs Zoladex. Reply Cancel Cancel. Reply Up 0 Down Cancel. FillSaid over 5 years ago. RK1 over 5 years ago in reply to FillSaid. Alwaysatgolf over 5 years ago. RK1 over 5 years ago in reply to freefaller. Hi Freefaller My hubby was told by his consultant that Prostap is not as effective as other hormone meds like Zoladex and Gorselin, but that it is prescribed as standard treatment now as it is cheaper.
Maggie May 55 over 5 years ago in reply to RK1. Maggie May 55 over 5 years ago in reply to freefaller. Coronavirus is having a huge impact on people living with cancer. Please support our emergency appeal. Ask an expert. More from us. Cancer information and support. Get involved. In your area. World's Biggest Coffee Morning. About us. Terms and conditions. Privacy policy. I have actually lost weight since this time last year 18kg despite the ADT, probably because of adopting a low-carb diet to tackle the diabetes I was diagnosed with then.
As well as the diabetes, since going on ADT I have diagnosed with osteoartritis both knees and have developed a trigger thumb and finger, but perhaps that is because I am more willing to go to the doctors these days. I've been on 3 monthly injection of Prostap for 2 years now i'm told it will be for years , my 'boobs' have enlarged a bit and i've put on weight around the middle and have had some but not many hot flushes.
Not had any real problems that have affected me in a negative way. In a strange way it's reassuring to have the hot flushes as I know the Prostap is working! Greetings all. Many thanks for your responses and stories, it's comforting to know that there are others in the same boat, even if none of us want to be here. Had a long chat with my GP yesterday, who is most understanding, and we agreed that although Zoladex may not be what you want to live with, I am tolerating it, and whilst a move to Prostap may not bring about any changes, we agreed to leave well alone and stay with Zolly.
It appears that the greatest complaint about Zolly is the size of the the injector and the subsequent pain and bruising, however, as all three of our Practice Nurses are brilliant at injections, I've never had any issues on this score. So it's Zolly and carry on for the next two years. What fun. May everybody improve soon and have a great Many regards. I have to say I am amazed that I keep hearing people talking about the pain of a Zoladex LA injection.
I have now had four, and have never suffered any pain, have had slight bruising but no pain. My nurse always sprays the area with a freeze spray which numbs it, so I guess anyone out there who is feeling pain should ask whoever is administering the injection to use a freeze spray first.
No problems here either with Zoladex but not all health trusts use freezer spray like mine. Some use a cream and some use nothing at all! Zoladex is fine with some sort of local anaesthetic. If administered incorrectly it can be painful and ineffective. In my experience, the worst by far is Degarelix and the easiest has to be Decapeptyl.
Click through to become a member and gain access to support, information and real time replies. I'm interested in conversations about diagnosis treatment living with cancer and I want to talk about treatment options advice side effects surgery radiotherapy hormone therapy sex life diet anything.
Know exactly what you want? Email this conversation Print this conversation. Posted 09 Jan at However, last week I received a letter from my GP surgery informing me that from now on, all Zoladex users will be transferred onto Prostap. This decision has been made after consultation with the Specialists at the local hospital which has an excellent reputation for RT treatments , and the local Care Commissioning Group.
I've spent the last week hunting for info on Prostap, and whilst I can find data sheets and other technical information, there seems to be little from users or real world interested parties. So is there anyone out there with real world experience of long term use of Prostap? Have you switched from Zoladex? What was the change like? Zoladex is FDA-approved to treat advanced breast cancer. This is a type of cancer that begins in the breasts and then spreads to other parts of the body.
Advanced breast cancer may extend to the lymph nodes, which are mainly located on the sides of the neck and groin, and beneath your armpits. Advanced breast cancer can also extend to other parts and organs of the body, such as the bones, liver, or brain. Zoladex is used as a palliative treatment to help ease symptoms such as bone pain. In a clinical study of people with advanced breast cancer, Zoladex was compared with an oophorectomy surgery to remove one or both ovaries.
Zoladex is FDA-approved to treat endometriosis , a condition in which the tissue that lines the inside of your uterus womb grows outside the uterus. The parts of the body that endometriosis most commonly involves are the:. It may be referred to as an endometrial lesion. Because this tissue acts like normal uterine tissue, it thickens and then breaks down during each menstrual cycle period.
This can cause symptoms such as extreme bleeding and painful periods. In a study of people who had endometriosis, Zoladex was compared with another drug used for endometriosis called danazol. The researchers looked at how well each medication worked to reduce endometrial lesions. This type of cancer starts in the prostate gland , which is located between the penis and bladder.
Zoladex is used with another drug called flutamide to treat this type of prostate cancer before and during radiation therapy. Radiation therapy is a kind of cancer treatment that kills cancer cells using concentrated beams of radiation. In a clinical study , people took Zoladex, the drug flutamide, and radiation therapy, or radiation therapy only. Zoladex is also FDA-approved to treat advanced prostate cancer.
Zoladex is used as a palliative treatment to help ease symptoms such as bone pain and trouble urinating. The medication also works to improve the quality of life for people with advanced prostate cancer.
In clinical trials , Zoladex was compared with orchiectomy surgical removal of the testicles. There was no significant difference in how long people who received Zoladex survived compared with people who had an orchiectomy.
There was also no significant difference in the lowering of a hormone called testosterone to castration levels. Zoladex is approved by the FDA to treat abnormal uterine bleeding. With this condition, you menstruate bleed at times other than during your normal menstrual cycle. It may be very light or heavy, occur for a long time, and occur often. Zoladex is used to thin the lining of your uterus before an endometrial ablation.
This is a procedure in which the lining of your uterus is removed. A clinical study randomly assigned women to receive either Zoladex or an injection of a placebo treatment with no active drug. This was followed by an endometrial ablation.
In addition to the uses listed above, Zoladex may be used off-label for other uses. Uterine fibroids are noncancerous growths in the walls of the uterus. Some women who have uterine fibroids have symptoms such as heavy menstrual bleeding and pain in their uterus. The American Academy of Family Physicians recommends Zoladex as an option to decrease fibroid size before a surgery to remove them.
Zoladex blocks the hormones that cause menstruation, which may help relieve symptoms of PMDD. The International Society for Premenstrual Disorders states that Zoladex and other drugs in the same drug class may be options for short-term treatment of PMDD for some women. You may wonder how Zoladex compares with other medications that are prescribed for similar uses. Here we look at how Zoladex and Lupron Depot are alike and different.
Although they contain different active drugs, Zoladex and Lupron Depot work in the same way. They both block production of certain hormones, including estrogen and testosterone. Both medications lower levels of these hormones in the blood. Zoladex and Lupron Depot are used as palliative treatments to help ease symptoms such as bone pain and trouble urinating.
Lupron Depot is also approved to treat uterine leiomyomata fibroids, which are noncancerous growths. Specifically, Lupron Depot is used along with iron therapy to help improve anemia low iron in the blood in people with this condition.
Both Zoladex and Lupron Depot must be given by a healthcare provider, but the medications come in different forms. Lupron Depot comes as a suspension liquid.
A healthcare provider gives it as an injection into the muscle intramuscular of your buttocks, shoulder, or thigh. You may receive a Lupron Depot injection every 1, 3, 4, or 6 months. Although Zoladex and Lupron Depot contain different drugs, they work in similar ways.
Therefore, these medications can cause some similar and some different side effects. Below are examples of these side effects. These lists contain examples of mild side effects that can occur when treating prostate cancer with Zoladex, with Lupron Depot, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur when treating prostate cancer with Zoladex, with Lupron Depot, or with both drugs when taken individually. A retroactive study was done to compare Zoladex with Lupron Depot in men with advanced prostate cancer.
Specifically, the researchers compared men who received Zoladex with men who received Lupron Depot. The goal was to see if either medication was better at lowering a hormone called testosterone to castration levels.
In the study, there was no difference in the results between men who received Zoladex and those received Lupron Depot. Zoladex and Lupron Depot are both brand-name drugs. There are currently no generic forms of either drug.
Brand-name medications usually cost more than generics. According to estimates on WellRx. But this may vary based on how often you receive Lupron Depot. Other drugs are available that can treat your condition.
Some may be a better fit for you than others. They can tell you about other medications that may work well for you. Note: Some of the drugs listed here are used off-label to treat these specific conditions.
Examples of other drugs that may be used for the palliative treatment of advanced breast cancer include:. Examples of other drugs that may be used to treat endometriosis include:. Examples of other drugs that may be used to treat prostate cancer include:. Examples of other drugs that may be used to treat advanced prostate cancer include:. Like Lupron Depot above , the drug tamoxifen Soltamox has uses similar to those of Zoladex.
Zoladex contains the active drug goserelin. Tamoxifen itself is the active ingredient in tamoxifen. Zoladex works by blocking the production of certain hormones, including estrogen and testosterone. Tamoxifen works in a different manner. Tamoxifen blocks the effects of estrogen, including growth in breast tissue. Zoladex and tamoxifen are both used to treat breast cancer but contain different drugs.
These lists contain examples of mild side effects that can occur with Zoladex, with tamoxifen, or with both drugs when taken individually when treating breast cancer. These lists contain examples of serious side effects that can occur with Zoladex, with tamoxifen, or with both drugs when taken individually.
Zoladex is a brand-name drug. Tamoxifen is a generic medication. The usual recommended dosage of Zoladex for the palliative treatment of breast cancer is a 3. The usual recommended dosage of Zoladex for endometriosis is a 3. The usual recommended dose of Zoladex for prostate cancer is a 3.
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